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Vacation rentals in Isla Mono

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Isla Mono

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious living area features a comfortable sofa and two accent chairs surrounding a striped area rug. Floor-to-ceiling windows offer panoramic views of the ocean and surrounding islands, while a flat-screen TV is positioned on a low console for easy viewing.
Villa in Boca Chica

Sand Dollar Villa by the sea at Boca Chica Panama

Sand Dollar Villa by the sea This beautiful, very private retreat boasts panoramic views and direct access to a beautiful beach and sheltered bay. Located in Boca Chica, it is only 45 minutes from Panama’s second largest city, David. From your doorstep, you can enjoy island hopping in an archipelago of unexplored islands, or you can choose to soak in the sun on your very own private beach. Sand Dollar Villa offers the perfect décor for gracious living and entertaining in a magical setting!

4.95 out of 5 average rating, 112 reviews
Top guest favorite
Home in David

HarveyHouse: safe, quiet, 3-bedroom house

Superhost, Guest Favorite and in the top 10 percent of Airbnb listings. Entire house in David, a quiet residential area going up La Perla, at the foot of Cerro de la Cruz. Three bedrooms, three bathrooms, and air conditioning in each bedroom and in the living room. No neighbors behind: just the green of the hill. It accommodates six people. Parking within the perimeter, with electric fence and cameras. Keys in a lockbox: Check in whenever you arrive. Well-maintained, clean and quiet house.

4.91 out of 5 average rating, 23 reviews
Top guest favorite
A serene pool area features a clear blue pool surrounded by tiled landscaping. Two white lounge chairs and a small table are positioned by the poolside, offering a relaxing spot. Lush greenery and a residential building are visible in the background under a bright blue sky.
Guesthouse in David

Pool House with Shared Pool Access

Pool House is a fully private space on a shared gated property. NOTE: We, the owners of the property, live in the Main House full time. If you have questions/need recommendations, we are available! Shared spaces on property: Pool, front yard, back walk way Local suburb, with bus and taxi access into town and plenty of parking if you choose to drive. 45 minutes from Boquete, 1 hour from Boca Chica and 2 hours and 1 hour boat ride to Bocas Del Toro, this location is a day-tripper's dream!

5.0 out of 5 average rating, 82 reviews
Top guest favorite
Apartment in David

Spacious balcony | 2 in the heart of David

Enjoy David from a modern 2-bedroom apartment designed for executives and families. Start your day with a coffee on your spacious balcony, relax with a movie in the cozy room, or just a hike to get to know the city. With a strategic location 2 minutes by car from the Via Interamericana and Plaza Terronal and 5 minutes from Federal Mall. Close to restaurants, plazas and shops, with easy connection to Boquete, Cerro Punta, the border with Costa Rica and other Chiriquí destinations.

5.0 out of 5 average rating, 8 reviews
Top guest favorite
A spacious room is visible through an open door, featuring a double bed with clean linens and a simple design. Natural light illuminates the area. A handcrafted wooden bench is placed in front of the bed. A potted palm adds a touch of greenery to the setting.
Guest suite in David

CasaMonèt

Suite with separate entrance: covered parking, double bed, bathroom, kitchenette and desk. Your personal space in the heart of David. It has split air conditioning, a ceiling fan, a TV with Netflix access, free WiFi internet, blackout curtains, a water reserve tank, hot water, a kitchenette equipped with an electric stove, a refrigerator, a coffee maker, a microwave, and basic utensils. It does not have a laundry room, electric generator, or soundproofing.

4.97 out of 5 average rating, 574 reviews
Guest favorite
Apartment in David

Escape with a panoramic view

Welcome to Escape with panoramic views, a modern and cozy apartment in Santa Cruz Tower, David. Enjoy a spectacular view from the balcony, queen size bed, air conditioning, desk, Wi-Fi, private bathroom and hot water. Located in a quiet area, but minutes from shopping malls such as Federal Mall and Plaza Terronal, restaurants, supermarkets and businesses. It also has direct access to Boquete, Chiriquí's most popular mountain destination. English or Spanish!

4.95 out of 5 average rating, 86 reviews
Top guest favorite
Farm stay in Boquete

Muy Boquete @ Boquete Bees and Butterflies

More than a stay an experience to promote the biodiversity of Panama. Panama's largest butterfly gardens, pollinator friendly coffee estate and birding paradise. We offer tasting activities and tours and our conservation focused butterfly experience is included in the farm stay. Our mission is to promote the conservation of Panamas biodiversity for the benefit of all and to demonstrate the superiority of sustainably produced hondy, coffee and wines.

4.93 out of 5 average rating, 382 reviews
Top guest favorite
Home in Los Algarrobos

Cozy and relaxing house with a terrace

Relax with the whole family in this quiet place, just 10 minutes from downtown David and 25 minutes from the tourist Boquete. Close by you'll find shopping malls, restaurants and services, but far enough away from the hustle and bustle of the city. A safe, comfortable space full of details to enjoy your stay. Safe house with 3 bedrooms, Café-Bar style terrace, patio with barbecue and gazebo, air conditioning and all the amenities to enjoy your stay.

4.95 out of 5 average rating, 184 reviews
Superhost
Home in Boca Chica

Stunning seaside villa with pool and jacuzzi

Wake up to these second to none ocean views that are always changing with high tide and low tide. The house is located inside the Hermosa Bay residence on the front line of the beach to which the residents have private access. Spacious with all amenities, including a jacuzzi, BBQ and three different fitness machines. The house uses solar energy so never suffers from power outage. The rental comes with usage of the remote controlled garage.

5.0 out of 5 average rating, 3 reviews
Superhost
The property features a spacious beachfront villa, framed by lush palm trees and open grass areas. A vibrant red roof contrasts with the white exterior, and the shimmering ocean is visible in the background, providing a serene coastal atmosphere.
Home in Playa Nanzal

Private Beachfront Getaway

Forget your worries in this spacious and serene space. Its seclusion is its charm. Escape from the busy city of David and kick back in our private beachfront property! There are little to no lights nearby, making for extraordinary sunsets/sunrises and star gazing. Whether you are a family looking to get away in the summer, a group of friends celebrating a birthday, or just looking for a break from life, this is the spot.

4.86 out of 5 average rating, 57 reviews
Top guest favorite
A private deck features two modern chairs with a small table between them, positioned on a textured area rug. A custom-built jacuzzi is visible in the background, surrounded by a wooden railing. Natural light floods the indoor living area through expansive glass doors.
Cabin in Boquete

Mundo Novo Casita @ Finca Panda

Mundo Novo is one of our new, one-room casitas and has one of the most incredible views on the property. Perfect for couples, singles or family with a small child, Geisha sleeps 2 people comfortably in one king bed (maximum 3 guests when using sofa). Geisha was designed with every amenity needed to have a perfect and relaxing stay. Custom-built jacuzzi, fire-pit, kitchen, incredible shower, high-speed WiFi and more

5.0 out of 5 average rating, 11 reviews
Top guest favorite
Cabin in Jaramillo

Coffee Cabins - Cabin 2

Welcome to the Coffee Cabins. This is one of four stunning A-frame cabins perched on the side of a mountain in the middle of a coffee field. You’re literally surrounded by coffee, both on the trees and in your kitchen with the complimentary coffee grown right here on the farm. Enjoy larger than life views to both the north towards the continental divide and to the west framing Volcan Baru, Panama’s highest peak.

4.98 out of 5 average rating, 54 reviews

Popular amenities for Isla Mono vacation rentals