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Vacation rentals in Hampton County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Hampton County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Varnville
5 out of 5 average rating, 20 reviews

Hank and Margie's Place

“PEACEFUL!! Nestled in the Lowcountry, a COZY LOOK AND Big City FEEL” – “Hank and Margie’s Place” This home is in a charming quiet neighborhood off Hwy 63/ 64, at the end of a cul-de-sac. "Perfect" for traveling construction/maintenance crews, health care professionals. Less than 1 mile to 1 local hospital, 10 Miles from Allendale County, 24 Miles from Colleton Regional, 44 Miles from Beaufort Memorial. Accommodates comfortably 4 Guests - 4 BR, 2.5 BA, FULL HOUSE GENERATOR & Very CLEAN.

Guest favorite
Home in Yemassee
4.94 out of 5 average rating, 17 reviews

Private Historic Home in Downtown Yemassee

Historic bungalow located just minutes from I-95 and a short drive to Beaufort. This cozy house is perfect for weary travelers or weekend getaways. Enjoy inviting living spaces, a fully equipped kitchen, and a large private backyard. Sit on the front porch under the grand live oaks or gather around the fire pit for a relaxing evening. Whether you are attending a wedding, graduating a Marine, antiquing, or hunting/fishing nearby, this is the place for you. Extended stays are welcome as well.

Guest favorite
Home in Estill
4.96 out of 5 average rating, 75 reviews

The Cottage

Reconnect with loved ones in this family-friendly place-- a peaceful setting in the South Carolina Low Country. We are centrally located in Estill, SC off of hwy 321. Our home is ideal for visiting hunters 🦌 (some of the best hunting in the state), tourist 📸, golfers⛳, or anyone desiring a peaceful escape🧘🏾‍♀️. Our home is clean, newly renovated, cozy, and fully electric. Explore nearby Lake Warren State Park, Beaufort, Hilton Head Island, and Savannah. Our home is ready for you!

Superhost
A rustic red cottage with a metal roof is set amidst lush greenery. The structure features a central porch supported by wooden beams. Nearby, a simple wooden fence encloses a grassy area, adding to the serene rural ambiance.
Cottage in Ridgeland
4.9 out of 5 average rating, 31 reviews

Farmhouse Cottage

Stop off I95 - 10 mins. Quiet tranquility on 60 Acres. Wide open spaces. Perfect for a solo wellness retreat or romantic escape. Penelope Properties Inc. See the stars above at night. Be Still. Walk the 1 mile fitness trail. Or bring your easel and paint the day away. Read a good book with all the windows open and pasture breezes blowing through. Close to Charleston, Beaufort, Savannah or Bluffton and Hilton Head. Plus area hunting lodges. Starlink Wifi - Cottage close to private house

Superhost
A comfortable living area is furnished with a dark leather sofa set and a round coffee table. Decorative pillows add texture, while a lamp and a television provide functionality. The hardwood floor complements the rich tones of the furniture.
Home in Estill
4.76 out of 5 average rating, 50 reviews

Cheerful 3 bedroom 2 bath residential home

Have your morning coffee on the front or back porch. Family dinner in the formal dining room or a BBQ in the back yard. This home sits on a 1 acre lot. It has hardwood floors throughout and carpet in the bedrooms. Explore nearby Beaufort, Hilton head, or Savannah Georgia which are all about 49 minutes from this location. Locals boast of hunting being one of the best in the state. Family reunions, girls or a boys trips, this beauty is clean functional cozy and ready for you!

Guest favorite
An aerial view showcases a spacious 4BR home set on 2 acres. Surrounding greenery includes trees and open lawn areas, with pathways leading to the main entrance. Adjacent structures and a gravel road are visible in the background, emphasizing the property’s serene setting.
Home in Yemassee
4.94 out of 5 average rating, 82 reviews

Lowcountry Orchard Getaway

Anderson Orchards – A Lowcountry Retreat Relax in this 4BR home on 2 acres with a bridge, oak tree, muscadine vines, pear, and pecan trees. Ideal for families or groups (sleeps 12+), it’s a peaceful retreat near top destinations: Beaufort – 40 min (historic downtown) Hilton Head – 1 hr (beaches, golf) Savannah – 1 hr (riverfront, nightlife) Charleston – 1 hr 15 min (historic charm) Parris Island – 45 min (boot camp grads) Plenty of space to relax and explore!

Guest favorite
Home in Early Branch
4.88 out of 5 average rating, 118 reviews

The Pine Hideout

Just a quick jump from 95. Enjoy the sounds of nature. Surrounded by big pine trees. Very private. Home sits off the beaten path and tucked in. Only 2 miles off 95 for travelers! Plenty of room for trailers or multiple cars. Close to Beaufort and Paris island. Hilton Head island, Hunting Island, Edisto beach, Charleston and Savannah, all with in an hour, with beautiful scenery to make any drive enjoyable! Live oaks and Spanish moss umbrella the roads.

Guest favorite
A softly lit Tiny House is nestled beneath a moss-draped tree, creating a serene ambiance at night. Reflections can be seen in the water nearby, enhancing the tranquil setting. The surrounding grass is lush and well-maintained, contributing to the peaceful rural environment.
Farm stay in Yemassee
4.97 out of 5 average rating, 117 reviews

“Tiny house” nestled on beautiful farm

We are less than 1 mile off of I-95 in the Low Country of South Carolina. Our 62 acre farm is nestled in the “middle of nowhere, but close to every where”. We are located close Beaufort, Charleston and Savannah! Our Tiny House, which used to be our feed shed, offers beautiful scenery from the Red barn, Moss draped Live Oak trees, Pecan Grove, horses, goats, free range donkeys and more. We have a brand new Bathhouse with a full bath. Washer & Dryer too!

Top guest favorite
Home in Yemassee
5 out of 5 average rating, 6 reviews

Riley Manor Quiet Neighborhood•Large Backyard

Kick back and stay a while in this spacious, fully equipped 3-bedroom home. Conveniently located just minutes from I-95 for easy on and off access. This home is designed for families and travelers alike, our space features comfortable living areas, a full kitchen for home-cooked meals, and the peaceful atmosphere that only the Lowcountry can provide. After a long day of exploring the coast, return to a quiet neighborhood where you can truly unwind.

Top guest favorite
Home in Furman
5 out of 5 average rating, 12 reviews

Superhost | Lowcountry Comfort | 3 BR | 1 GB Wi-Fi

Experience relaxed Southern comfort in this single-level 3BR/1.5BA Superhost home on a quiet 1-acre lot in Furman, SC, less than 1 minute (about 0.2 miles) from Town Hall and just off Hwy 601. Once home to Lizzie Young, Hampton County’s first female mayor and Furman’s first African American mayor (1990–1999), this historic stay blends local Black history, modern comfort, immaculate cleanliness, fast 1GB Wi-Fi, and peaceful surroundings guests love.

Guest favorite
A spacious wooden deck is seen, surrounded by tall trees, providing a serene outdoor space. Two red chairs and a glass table are positioned on one side, while a wooden bench offers additional seating. Natural light filters through the greenery, enhancing the tranquil setting.
Cabin in Early Branch
4.93 out of 5 average rating, 54 reviews

"Tranquil Tiny Cabin Retreat"

"Experience the tranquility of our secluded tiny cabin in Early Branch, SC. Surrounded by nature, this charming retreat offers a peaceful escape. Relax by the fire pit, fish in the private pond, and enjoy the cozy interior with small rooms, bathroom, and kitchen. Ideal for those seeking serenity and intimacy in a rustic setting. Book now for a unique getaway unlike any other."

Superhost
A tranquil dirt road is framed by towering trees and dense shrubs, with a carpet of fallen leaves underfoot. The path appears secluded, inviting leisurely exploration into the natural surroundings.
Campsite in Pineland
5 out of 5 average rating, 4 reviews

Sweet spot in the woods, 50amp with water & septic

We have over 12 acres of secluded land just 20 minutes from I-95. We are at the end of a dirt road. Come and unwind, take a leisurely hike through the woods visit our sheep and goats. We provide fresh filtered well water and a hookup for your camper or RV. There are no public bathroom facilities but there is septic access. This is a back in spot.

Popular amenities for Hampton County vacation rentals