
Vacation rentals in Guthrie County
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Top-rated vacation rentals in Guthrie County
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Small Town Mansion
Step into the charm of this beautiful early-1900s Sears & Roebuck home—truly a one-of-a-kind getaway. Located in the heart of Guthrie Center, you’ll be just 15 miles north of I-80 and 8 miles west of Lake Panorama. Enjoy peaceful mornings on the front porch or stretch out and relax in the spacious living room. A large and thoughtfully curated book collection awaits any reading enthusiast. The entire home is yours to settle into, unwind and make your own! Ample parking-double car garage & street.
4.93 out of 5 average rating, 179 reviews
Cabin w/ Hot Tub + Fire Pit + Private Trails
Looking for a place to slow down, reconnect, and make memories? Located 30 minutes from WDM and 90 minutes of Omaha, this modern cabin on a private wooded property is designed for couples, families, and small groups. Guests love: • Hot tub under the stars • Views from every room • Outdoor fire pit and fireplace • Fully stocked kitchen • River access and nature trails • Peaceful setting with easy access to small-town attractions Experience the ultimate retreat and choose your own adventure.
4.94 out of 5 average rating, 113 reviews
Peaceful Stay 3.63 Acres 2 Minutes to Lake & Golf
Escape to this peaceful Panora, IA retreat set on 3.63 acres of private yard. The bright, open-concept main level brings the living, dining and fully equipped kitchen together. The home has three bedrooms, two full baths and one half bath, plus a garage for convenience. Step outside to the back porch to watch amazing sunsets while grilling dinner, or go out on the lawn during the summer where yard games provide outdoor fun. Families are provided with kids’ toys, games, and a pack ’n play.
5.0 out of 5 average rating, 29 reviews
Seely Creek Cabin Getaway and Hunting Lodge
Seely Creek Cabin is a romantic getaway, a fabulous hunting destination, and a relaxing weekend spot! The cabin is nestled on 40 acres - 20 being wooded and another 20 open including a fully stocked pond and a walking trail! This beautifully unique property comes equipped with a fully stocked kitchen including all cooking necessities (except for food), a smart tv, wifi, games and cards in the entertainment center, as well as 3 comfy queen sized beds with all linens you would need!
4.97 out of 5 average rating, 100 reviews
Cozy Country Container Stay w/ Hot Tub & Fire Pit!
Cozy 1-bed shipping container home in rural Stuart, IA. Perfect for couples or solo travelers. •Sleeps 2 • Queen bed • Full kitchen & Bath •Hot tub • Fire pit • Grill •Shared pond for fishing & scenic views. •Friendly horses & dogs on site (winter months may vary) (guests can interact) please treat them with kindness. •Peaceful country setting—. perfect for relaxing & stargazing •You may see a critter or two—. true country living!
4.99 out of 5 average rating, 74 reviews
Fire Creek Homes
Our condo at Lake Panorama National Golf Course is a quiet retreat for the entire family or golf buddies. Located on the fairway of Hole #5 with a view of the lake. 3 bedrooms and 3 bathrooms with laundry on site makes this a comfortable experience in our 1,900 SF condo. Need more space? Check out our additional rental, just a few units away: https://www.airbnb.com/rooms/1622458927125168285?unique_share_id=93de812c-23a0-42c0-8eca-0a3e754349f7&viralityEntryPoint=1&s=76
4.96 out of 5 average rating, 25 reviews
The Rookery Cottage - Access scenic hiking trails
This rustic cottage is a quiet retreat in the heart of the Middle Raccoon River Valley. Situated on a private acreage within Whiterock Conservancy, guests can easily access 40mi+ of scenic hiking and mountain biking trails, float the nearby river, or enjoy dark sky viewing. A "rookery" is a nesting site for herons, a bird that prefers quiet, undisturbed habitat near water. And so the Rookery Cottage seeks to provide a natural escape from the daily grind.
4.98 out of 5 average rating, 335 reviews
Warm, cozy 4 bedroom lodge-style country home
Located in the country just 8 miles north of I-80 Exit 76 between Des Moines and Omaha, this lodge-style, 4 bedroom, 2 1/2 bath home is the perfect place for a quiet weekend getaway. The home is perfectly decorated with a rustic, mountain cabin-y feel, with lots of seating for dining or playing games together, or relaxing on couches and chairs in the living room. There is a large patio outside to enjoy grilling or your cup of coffee in the sunshine.
4.85 out of 5 average rating, 34 reviews
Feels Like Home Studio
A quiet and relaxing environment from the quick pace of your daily routine. Great location near Lake Panorama and on the Lake Panorama National Golf Course. Only blocks away from the club house and swimming pool. This is a wonderful place to get away from the city and enjoy a walk along the beach, a quick dip in the lake, or a round of golf. There are local establishments like The Penoach Vineyard or The Port with evening dinning and musical events.
4.91 out of 5 average rating, 45 reviews
Crafty Cottage at Lake Panorama
Relax with the whole family at this peaceful Craftsman cottage on beautiful Lake Panorama, just 50 minutes from the Des Moines metro and 90 minutes from Omaha. Located in a private lake community featuring three beaches, hiking trails, playgrounds, tennis, basketball, award-winning golf courses and a dog park, this off-water property on a wooded lot with partial lake views welcomes you into a relaxing getaway the moment you open the door.
5.0 out of 5 average rating, 28 reviews
Water Front Lake House on Gorgeous Lake Panorama
This is a beautiful, comfortable water front lake home on gorgeous Lake Panorama. Spacious rooms with lots of windows allow you to enjoy the lake views any time of day or night. There is outdoor seating, a grill, and a fire pit on the patio. Two kayaks and a paddle boat are included, and there are boating and jet ski options as well. The property conveniently borders the lake, and the 18 hole National Golf Course is minutes away.
4.94 out of 5 average rating, 16 reviews
The 1894 by Doe A Deer | 2 br, 1 bath apartment
Welcome to The 1894 by Doe A Deer - a newly renovated 2 bedroom spacious apartment located in historic downtown Stuart! Enjoy restaurants, boutiques and coffee just steps from the front door. Relax and enjoy the view from your new favorite small town spot. Perfect for getting ready with your wedding party, families, girls trips, anniversaries & more! We can’t wait to host you!
4.97 out of 5 average rating, 191 reviewsPopular amenities for Guthrie County vacation rentals
Other great vacation rentals in Guthrie County

Menlo Farmhouse
4.76 out of 5 average rating, 46 reviews
Beautiful Pine Log Cabin at Lake Panorama
5.0 out of 5 average rating, 10 reviews
Beautiful waterfront House at Lake Panorama
4.94 out of 5 average rating, 16 reviews
Spacious Getaway Townhome on Lake Panorama/Golf
4.97 out of 5 average rating, 39 reviews
Bright 4BR Bungalow Sleep 12 near Des Moines & i80
4.69 out of 5 average rating, 85 reviews
Charming Getaway
4.64 out of 5 average rating, 11 reviews
Rustic country 2-bedroom SAWMILL with Free parking
5.0 out of 5 average rating, 3 reviews
Private Beach! Lakefront Cabin in Panora





