
Vacation rentals in Doña Ana
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Top-rated vacation rentals in Doña Ana
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Quaint casita for 2
*Sep 2025 New bed/Aug 2024 New A/C mini split* Quiet cul-de-sac and peaceful landing spot within minutes to NMSU and Old Mesilla. Easy access to I-10 and I-25. Close to golf courses, shopping and the beauty of Las Cruces and Mesilla. Private entrance to casita, patio with dining table and a cozy bedroom, bathroom with tub/shower, WiFi, coffee station, refrigerator with small freezer, microwave. Wonderful hiking trails nearby and less than 60 minutes to White Sands National Park and ELP Airport.

Matchbox desert oasis hot tub, pet friendly!
Come experience a spa like feel in the desert where tranquility awaits! This container home is new,clean,relaxing, romantic and comfortable! Surrounded by farm land, with a clear view of the Organ Mountains, makes the night extra special spending it in the hot tub on the private patio or in the beach like sand zen landscape. You can go explore the next door property enter the hen den feed the chickens along with ducks, turkey, goats and horses! Free farm fresh eggs with every stay! No farm smell

Tiny Cute Cubby in Telshor Hills, Private Entrance
The Cubby is perfect for overnight or short-term stays. Zero contact check-in and check-out. Access to central Las Cruces. Close to NMSU, Mesilla Valley Mall, major medical centers, and major event facilities. Located in Telshor Hills, a quiet neighborhood with plenty of mature trees and vegetation. Close proximity to observatory, minimal light pollution. Gorgeous views of Organ Mountains and Tortugas Mountain (A Mountain). Ten minute drive from historic Mesilla. Close to various hiking trails.

Luxury Southwest Retreat
Our home provides comfort, relaxation, and convenience in an invitingly decorated setting. Three rooms offer various sleeping arrangements to meet all of your needs. Choose from a king, queen, or twin beds. Fully equipped and thoughtfully appointed kitchen provides for all of your meal needs. Luxurious backyard with Adirondack chairs, gas fire pit, porch rocking chairs, and outdoor dining set allow for relaxing and socializing. Washer & dryer available, detergent and fabric softener provided.

Modern Luxury Home
This Luxury Modern Home is made to suit all guests! Whether you are looking for a weekend getaway or a place for work and play, this home has everything to offer in beautiful Las Cruces, NM. Located in a brand new neighborhood near Red Hawk Golf Course and multiple family-friendly parks. Guests can rest peacefully in one of 4 bedrooms and enjoy amenities such as an outdoor grill, outdoor living area, lawn games, board games, and most kitchen items. High-speed Internet included and SmartTVs.

Southwest Mexican Adobe Casa Historic District
This wonderful adobe home with refrigerated air is located directly in the heart of the city the Mesquite Historic District of Las Cruces. This Mexican home combines the neighborhood classic adobe style. Directly across the street is a Mexican cafe and a coffee shop. Seven minute walk to downtown which has wonderful pubs and restaurants. This home is located directly across the street from my other two casitas that are listed in Airbnb. Dog fee $10.00 which can be left on the table.

Desert Peaks Casita
This lovingly remodeled casita just fifteen minutes from downtown Las Cruces is open, spacious, and comfortably equipped for any length stay. Take in the views of the mountains, watch the birds, or relax in the hot tub under the stars. Hike to the Organ Mountains-Desert Peaks National Monument via an arroyo from the casita, take a dip in the pool, or rest in the peaceful and tastefully decorated space. It is a perfect place for a quiet getaway or as a base to explore the area.

Modern Accessorized 3-Bedroom
This fully-furnished modern home is perfect for weekend getaways or longterm stays. With latest in appliances and style, the Powder River Villa offers the comfort of home with a luxury feel. Stream Netflix in front of the stacked stone fireplace, decompress in the pebble rain shower, or simply relax on the back porch to the beautiful New Mexico sunsets. This stylish space can be the romantic escape you're seeking or comfortably fit your group of 7.

Cozy Casita w/private patio near Old Mesilla
This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Studio w/queen bed, pets ok, 3 min to Farmer's mkt
Wonderfully serene little studio with a full kitchen. The bed is a queen memory foam, so it is very comfortable. Bring your dog with you, there is a nice-sized, secure yard for your pooch. There is everything you need to cook a small meal on the apartment-sized electric stove and oven, the kitchen is complete with a fridge, coffee maker, toaster, utensils, dishes, pots and pans, and fresh farm eggs from your host's farm!

Cozy Casita De Mesilla (Mesilla Cottage)
Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Lovely Casita Suite (No Cleaning fee)
Unique place has a style all its own. New Casita in a new area close to professional Golf Course located at the foothills of the majestic organ mountains. Private entrance, kitchenette, living area that has a new sofa sleeper which can sleep up to 2 people. Has a private bedroom and private bathroom. Easy access to main highway that leads to shopping and restaurants.
Popular amenities for Doña Ana vacation rentals
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