Vacation rentals in Darlington County

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Top-rated vacation rentals in Darlington County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
The cottage is softly illuminated by string lights, creating a serene atmosphere in the yard. A charming fountain adds a soothing element to the outdoor space, complemented by a patio area featuring a red umbrella and a table among well-maintained greenery.
Guesthouse in Hartsville
4.83 out of 5 average rating, 35 reviews

Private Cottage, Guesthouse, Queen Bed & Kitchen

Charming, peaceful cottage just a short walk from downtown Hartsville. Ideal for work, visits to local schools, or a relaxing getaway. • Private driveway • Fast WiFi & workspace • Smart TVs & games • Fully equipped kitchen • Snacks, tea & coffee • In-house laundry • Outdoor seating • Dog-friendly We kindly ask that any pets are disclosed in your reservation. The pet fee helps cover additional time & care needed to clean so we may continue offering a pet-friendly space for all guests.

Top guest favorite
A single-story home is shown with a welcoming front porch and bright red door. The exterior is accented by black shutters and a white facade, surrounded by a grassy lawn with small trees. A clear blue sky with soft clouds is visible in the background.
Home in Hartsville
4.99 out of 5 average rating, 138 reviews

Manchester Place

Hartsville is a Charming Town with plenty of family activities, shops, and dining. Home is located in the quiet Fox Hollow subdivision which is just outside the city limits but still close to downtown. Robinson Nuclear Plant 10 min. Sonoco 7 min. Coker University 7 min. Downtown Hartsville 7 min. Carolina Pines Hospital 9 min. McLeod Hospital Florence 42 min. Byerly Park 9 min. Hartsville Center Theater 6 min. Governor's School for Science and Mathematics 9 min. Darlington Raceway 22 min.

Superhost
A bright living area is furnished with a light-colored sofa adorned with accent pillows. In front, a wooden coffee table rests on a soft area rug. The kitchen is visible in the background, showcasing modern appliances and an open layout that enhances the space's inviting feel.
Apartment in Florence
4.89 out of 5 average rating, 379 reviews

Kuker Carriage House-Sleeps 3-Downtown/Near I95&20

Kuker Carriage House was originally a barn that has been converted into apartments in the heart of the newly revitalized Florence downtown. This first floor unit was just fully renovated and is ready for you to enjoy, whether for a short overnight stop or a longer extended stay. This space is bright and open with lots of natural light and a fully enclosed private courtyard. Queen bed, twin daybed, full bath, Wifi and TV. Walkable to parks and restaurants. Just 4 miles from I95 and I20

Top guest favorite
The bedroom features a spacious bed with decorative pillows, flanked by two bedside tables with lamps. Soft lighting creates a calming ambiance. A door leads to an adjoining space, while light walls enhance the feeling of openness.
Home in Timmonsville
5 out of 5 average rating, 25 reviews

Comfy Suite Sleeps 4 Near I20&95

Suite Carolina is a newly renovated private guest suite located in a rural setting just minutes from Florence, South Carolina. This one-bedroom, one-bathroom suite offers comfort and simplicity with modern touches—perfect for an overnight stay or a longer visit. The space includes a queen bed, queen sleeper sofa, partial kitchenette, and a spacious master bath. Situated just 4 minutes off I-20, this spot is ideal for travelers or anyone seeking a home base with quick access to Florence.

Top guest favorite
The spacious living area features a comfortable gray sofa, accented with vibrant throw pillows. Two armchairs flank the seating arrangement, with a stylish coffee table at the center. A large TV is positioned against a wall, while bright windows provide ample natural light.
Bungalow in Hartsville
4.95 out of 5 average rating, 116 reviews

The Pelican House | 2-bdrm in H-ville w/King Bed!

The Pelican House is in downtown Hartsville, walking distance to Sonoco & Coker University. The main bedroom features a comfy king bed, 2nd bedroom has 2-twin beds, & additional sleeping is available on the flip out queen sofa bed in the living room. Sit & rock on the front porch, grill out on the propane grill, make meals in the stocked kitchen, or walk downtown to restaurants, bars, & shops. Kitchen table has seating for up to six. Covered parking is offered in the connected carport.

Guest favorite
A well-appointed sleeping area contains two beds, each dressed in light-colored bedding with decorative throws. A bedside lamp is positioned between the beds on a dark nightstand. Natural light enters through partially covered windows, highlighting the room's neutral tones and horse-themed wall art.
Barn in Society Hill
4.94 out of 5 average rating, 359 reviews

Burchs Carriage House

Private carriage house sitting adjacent to the most historic estate home in the lovely town of Society Hill. Separate entrance for guests which accommodates large horse trailers. Property caters to all animals! Kitchenette (microwave, toaster oven and hot plate), washer/dryer, Apple TV and wifi. Continental breakfast, wine/snacks provided. BBQ grill also. 2 stalls with paddocks. 12 x 12 and 10 x 12. Rooms are as they would be at your own home, separate from each other. See photo 13.

Top guest favorite
The cozy interior features rustic wooden beams and a blend of warm tones. A spacious bed is positioned against a wall with a peacock artwork. A kitchenette area is visible, alongside a small dining table and a television, providing a comfortable, multifunctional living space.
Farm stay in Timmonsville
4.95 out of 5 average rating, 682 reviews

The Cottage at Dream Acres & Petting Zoo I-95/I-20

The Cottage at Dream Acres is situated with its own private drive on our 8 acre working horse farm located near Florence SC at the I-20/ I-95 corridor, 5 mins off the highway. We are the 1/2 way point between NY & FL. Relax and unwind from a long roadtrip or take a weekend farm-stay getaway. All the amenities of a larger home with the convenience of a smaller space! Family Friendly; sleeps up to 4, newly renovated in 2020, petting zoo, outdoor fire pit, tree swing, picnic table!

Top guest favorite
A living area is shown featuring a large brown sectional sofa with decorative pillows. A green coffee table sits on a light-patterned rug, with a television displaying an underwater scene. The space is illuminated by soft lighting from a dining area visible in the background.
Guesthouse in Florence
4.98 out of 5 average rating, 860 reviews

Boho Private Downtown Stay Near I-95 & Hospital

Comfort, cleanliness, privacy, and personality! Perfect for overnight stays or longer terms. Come enjoy our Boho hideaway in the heart of Florence. Our place has all the amenities of a hotel with the comfort and privacy of your own home including covered parking for two vehicles. We are located within walking distance to downtown Florence and a 5 minute drive to all of the restaurants and shopping that Florence has to offer. Come stay at our guest house and make yourself at home!

Guest favorite
The kitchen features modern appliances, including a stainless steel refrigerator and an electric stove. Natural light fills the space through multiple windows. A wooden dining table is visible, accompanied by a set of chairs. A doorway leads to the outside.
Home in Hartsville
4.84 out of 5 average rating, 134 reviews

Quaint 2BR home w access to Black Creek & downtown

Our freshly renovated home sits in a family-oriented neighborhood only a mile from downtown Hartsville and Kalmia Gardens and includes access to Black Creek. This 600 sf home features 2 bedrooms, 1 bath, a full kitchen, washer and dryer and an open living area. Digital antenna reception for smart-tv and high speed wi-fi internet. Small dogs will be considered for stays on a case-by-case basis. Pet stays require prior approval from the hosts and will involve additional fees.

Guest favorite
A charming bungalow exterior is displayed, featuring a light-colored wooden facade with dark shuttered windows. A small porch with a railing is visible at the front, surrounded by neatly trimmed landscaping and a grassy area leading to the street.
Home in Darlington
4.84 out of 5 average rating, 134 reviews

Located 100 feet from The Darlington Raceway!

This cute little bungalow is located across the street from The Darlington Raceway. Just a few steps puts you at the door of the famous Joe Weatherly Stock Car Museum. We are also within walking distance to Manheim Auto Auction. The Raceway Grill, a favorite of Dale Earnhardt, is located across the street ! If you are here during the week, South of Pearl, Darlington's finest eating establishment, is located in uptown Darlington. WE DO NOT HAVE A STOVE OR WASHER/DRYER

Guest favorite
Home in Florence
5 out of 5 average rating, 7 reviews

3BR Group-Friendly Home | Great Location + WiFi

Welcome to your group’s home away from home in Florence, SC! This 3BR, 5-bed, 1-bath home is tucked away in the quiet Sherwood Forest neighborhood—offering a peaceful retreat with quick access to downtown, highways, and job sites. With cozy twin beds, high-speed WiFi, a fully equipped kitchen, and free parking, this home has everything your team needs to relax and recharge after a long day. Perfect for flexible and extended stays to suit your project timeline.

Top guest favorite
A charming poolside cottage is surrounded by lush palm trees and vibrant plants. The outdoor space features a dining set on a paved patio, providing a tranquil area for relaxation. The entrance to the cottage is easily accessible, enhancing the inviting ambiance.
Guesthouse in Florence
4.93 out of 5 average rating, 878 reviews

Cottage by the Pool: Close to Interstates

Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, full sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

Popular amenities for Darlington County vacation rentals