
Vacation rentals in Santa Cruz
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Santa Cruz
Guests agree: these stays are highly rated for location, cleanliness, and more.
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Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Cruz vacation rentals
Other great vacation rentals in Santa Cruz

Home in Trujillo Alto
5 out of 5 average rating, 4 reviewsPeaceful in Nature Casita Studio near San Juan.
Superhost

Apartment in Trujillo Alto
5 out of 5 average rating, 9 reviewsHermoso Apartamento - Full A/C

Home in Trujillo Bajo
4.84 out of 5 average rating, 113 reviewsCozy Studio #1 In The Heart Of Puerto Rico
Guest favorite

Apartment in Río Grande
4.92 out of 5 average rating, 12 reviewsSweet Ville
Top guest favorite

Guesthouse in Carolina
5 out of 5 average rating, 20 reviews“The Couples Escape”Great vibes, Location +Comfort
Guest favorite

Home in Hato Puerco
4.98 out of 5 average rating, 42 reviewsParadise Libre Expresion
Superhost

Home in Quebrada Grande
4.85 out of 5 average rating, 20 reviewsEl Encanto del Campo en la Puerta de la Ciudad
Superhost

Apartment in Carolina
4.76 out of 5 average rating, 90 reviewsApartamento cerca aeropuerto, playas y comercios.
Destinations to explore
- Carolina Vacation rentals
- Culebra Vacation rentals
- Saint Thomas Vacation rentals
- Saint Croix Vacation rentals
- Tortola Vacation rentals
- Luquillo Vacation rentals
- Rincón Vacation rentals
- Aguadilla Vacation rentals
- Santo Domingo Vacation rentals
- Punta Cana Vacation rentals
- San Juan Vacation rentals
- Las Terrenas Vacation rentals
- Yurt Rentals United States
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- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
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- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
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- Holiday Chalets United Kingdom
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- Holiday Apartments Australia
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- Big Cottages Australia
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- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
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- Pet-Friendly Vacation Rentals United States
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- Dog-Friendly Cottages United Kingdom
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- Flamenco Beach
- Rio Mar Village
- Mosquito Bay Beach
- Distrito T-Mobile
- Praia de Luquillo
- Playa del Dorado
- Playa de Vega
- Liquillo Beach
- Playa Mar Chiquita
- Playa Puerto Nuevo
- Playa Sun Bay
- Los Tubos Beach
- Playa el Convento
- Beach Planes
- Playa de los Cabes
- Toro Verde Adventure Park
- Playa Puerto Real
- Playa Maunabo
- Carabali Rainforest Park
- Coco Beach Golf Club
- Punta Bandera Luquillo PR
- Playa de Cerro Gordo
- The Saint Regis Bahia Golf Course
- Playa Las Palmas