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Enter dates and number of guests to see the total price per night.
Over 6,000 guest reviews for places to stay in Port St. Lucie, with an average of 4.8 out of 5 stars.

300+ places to stay

Entire condominium
Rating 4.34 out of 5114 reviews
PGA Resort Studio ...FREE Yacht★Clear Kayaks
3 guests · Studio · 2 beds · 1 bath
Pool · Wifi · Air conditioning · Kitchen
SUPERHOST
Private room
Rating 4.97 out of 539 reviews
Secret Garden Oasis w/ hot tub - Master Bedroom
2 guests · 1 bedroom · 1 bed · 1 private bath
Wifi · Air conditioning · Kitchen
Entire condominium
Rating 4.62 out of 581 reviews
PGA Condo plus FREE Yacht★Clear Kayaks
4 guests · 1 bedroom · 3 beds · 1.5 baths
Pool · Wifi · Air conditioning · Kitchen
SUPERHOST
Entire house
Rating 4.95 out of 5133 reviews
Newly Decorated Private Guest House
3 guests · 1 bedroom · 2 beds · 1 bath
Wifi · Air conditioning · Kitchen
SUPERHOST
Entire guest suite
Rating 4.57 out of 57 reviews
Pretty cottage. No children. One small dog ok
2 guests · 1 bedroom · 2 beds · 1 bath
Wifi · Air conditioning
Private room
Rating 4.65 out of 547 reviews
The Friar Escape
2 guests · 1 bedroom · 1 bed · 1 shared bath
Pool · Wifi · Air conditioning · Kitchen
Entire condominium
Rating 4.19 out of 577 reviews
Poolside Studio Apartment and FREE Yacht .. Kayaks
2 guests · Studio · 2 beds · 1 bath
Pool · Wifi · Air conditioning · Kitchen
Private room
Rating 4.71 out of 57 reviews
The All White Room
1 guest · 1 bedroom · 1 bed · 1 shared bath
Wifi · Air conditioning · Kitchen
SUPERHOST
Entire apartment
Rating 4.93 out of 5112 reviews
Studio Steps from Heated pool. Close to I-95
4 guests · 1 bedroom · 2 beds · 1 bath
Pool · Wifi · Air conditioning · Kitchen
SUPERHOST
Private room
Rating 4.95 out of 557 reviews
Luxe Retreat:Bed & Breakfast | Salt Water Pool/Spa
2 guests · 1 bedroom · 1 bed · 1 shared bath
Pool · Wifi · Air conditioning · Kitchen
SUPERHOST
Entire house
Rating 5.0 out of 520 reviews
Key West Style Beach House
6 guests · 2 bedrooms · 2 beds · 2 baths
Wifi · Air conditioning · Kitchen
Private room
Rating 4.88 out of 58 reviews
Amazingly Bright and Roomy Florida Room
2 guests · 1 bedroom · 1 bed · 1 shared bath
Wifi · Air conditioning · Kitchen
SUPERHOST
Private room
Rating 4.93 out of 5112 reviews
Cozy Guest room with private entrance .
2 guests · 1 bedroom · 1 bed · 1 private bath
Wifi · Air conditioning
SUPERHOST
Private room
Rating 5.0 out of 513 reviews
UPSCALE Paradise. Stay and ENJOY. PRIVATE ENTRANCE
2 guests · 1 bedroom · 1 bed · 1 private bath
Pool · Wifi · Air conditioning
SUPERHOST
Private room
Rating 4.97 out of 529 reviews
Private 2 BR Suite with Pool in Home
4 guests · 2 bedrooms · 2 beds · 1 private bath
Pool · Wifi · Air conditioning · Kitchen
SUPERHOST
Private room
Rating 4.97 out of 537 reviews
Secret Garden Oasis w/hot tub- Family Suite -2 rms
4 guests · 2 bedrooms · 3 beds · 2 baths
Wifi · Air conditioning · Kitchen
SUPERHOST
Entire cottage
Rating 4.98 out of 559 reviews
Vacation Cottage of Port St. Lucie
4 guests · 1 bedroom · 3 beds · 1 bath
Wifi · Air conditioning · Kitchen
SUPERHOST
Private room
Rating 4.93 out of 5125 reviews
Private, Quiet & cozy guest suite / Pool
2 guests · 1 bedroom · 1 bed · 1 private bath
Pool · Wifi · Air conditioning · Kitchen
1 18 of 300+ places to stay
Enter dates to see full pricing. Additional fees apply. Taxes may be added. Free cancellation only applicable within 48 hours from booking.