Vacation rentals in Pickens County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Pickens County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Tiny home in Pickens

4.94 out of 5 average rating, 154 reviews

Lazy Bear Retreat by the Creek

The perfect romantic getaway! Come soak in our hot tub while listening to the water flowing. Lights surround our tiny house to create the mood. Lounge during the day in the sun. Want to stay in and eat? Enjoy our grill and table outside or cook inside. Want to eat out? Aunt Sue's and Pumpkintown General store are both so close. Both have delicious homemade meals! Victoria Valley Vineyards is perfect for wine tasting. We provide a year long state park pass. Tablerock state park minutes from you

Dec 31 – Jan 7

€ 141 per night
Guest favorite

Apartment in Easley

4.93 out of 5 average rating, 398 reviews

Countryside apartment near Appalachian foothills

This cozy home away from home is a completely private apartment located in the Upstate South Carolina. The private 2 bedroom apartment has its own entrance separated completely from the main home. There is also covered parking available for the guests. Centrally located to places such as the Sassafras mountain that is the highest point in SC and TN and Clemson University. Caesars Head and Table Rock are only 20 min away. A lovely golf course is located right around the corner, 4 min. away.

Oct 22 – 27

€ 93 per night
Guest favorite

Guest suite in Central

4.97 out of 5 average rating, 141 reviews

Elfwing Carriage House

Bright & comfortable studio apartment located in a quiet family neighborhood in the country, yet minutes to town. We are an easy 15 minute drive to Clemson, less than 5 miles to SWU, 7 miles to Duke Energy. Smart location for the mountains & lakes, visiting colleges, and graduation. Tiger tailgate space available for an additional fee. Hikes, waterfalls, 12 Mile river & Lake Hartwell are nearby. Friendly dogs are fenced or in our home. Come enjoy neighborhood & country living at its finest!

May 28 – Jun 2

€ 109 per night

Popular amenities for Pickens County vacation rentals

Other great vacation rentals in Pickens County

Guest favorite

Shipping container in Easley

4.99 out of 5 average rating, 180 reviews

Scenic lakefront home w/ dock, fire pit, + kayaks

Mar 8 – 15

€ 372 per night
Guest favorite

Home in Pendleton

4.89 out of 5 average rating, 125 reviews

Comfort & Convenience Close to Campus

Aug 22 – 29

€ 129 per night
Guest favorite

Cabin in Pickens

4.96 out of 5 average rating, 75 reviews

Hagood Mill Hideaway

Oct 11 – 18

€ 97 per night
Guest favorite

Cabin in Pickens

5.0 out of 5 average rating, 12 reviews

Spotted Deer Cabin-Brand New- Mountain Views

Jan 11 – 18

€ 139 per night
Guest favorite

Cabin in Pickens

4.97 out of 5 average rating, 77 reviews

Table Rock Retreat. Cozy cabin with hot tub.

Oct 5 – 12

€ 129 per night
Guest favorite

Cabin in Pickens

5.0 out of 5 average rating, 69 reviews

The Romantic Greystone Cottage

Feb 1 – 8

€ 126 per night
Superhost

Home in Liberty

4.94 out of 5 average rating, 34 reviews

3 Bed Home Overlooking Fishing Pond on 10 Acres

May 18 – 25

€ 128 per night
Superhost

Treehouse in Pickens

4.86 out of 5 average rating, 66 reviews

Branches Up Tree House Mountain Getaway

Feb 10 – 17

€ 134 per night
Guest favorite

Cottage in Central

5.0 out of 5 average rating, 90 reviews

The Wildflower

Dec 23 – 30

€ 127 per night
Guest favorite

Home in Easley

4.96 out of 5 average rating, 26 reviews

Respite House

Oct 6 – 13

€ 119 per night
Guest favorite

Townhouse in Pickens

5.0 out of 5 average rating, 18 reviews

Waterfall and Golf Course Views in Your Backyard

May 25 – Jun 1

€ 135 per night
Guest favorite

Camper/RV in Easley

4.96 out of 5 average rating, 73 reviews

Delightful 1-Bedroom RV/Camper

Apr 9 – 16

€ 90 per night

Destinations to explore