Vacation rentals in O'Fallon

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in O'Fallon

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Home in Saint Charles

4.98 out of 5 average rating, 483 reviews

301 Guesthouse SuperHost/Shop Discounts/Katy Trail

Our 301 Guest House is new and completely remodeled in 2018! It’s ideal for one or two people with beautiful furnishings, great queen bed, lots of amenities, full kitchen, with big back yard and patio to enjoy outdoors too! Cable and FAST WiFi! Enjoy light Breakfast! BEST location, Great events year round within walking distance, with being only about 2 blocks from S. Main St, where there are about 100 gift shops n restaurants! Katy Trail is so close, with Spring, Summer, Fall and Xmas events!

Sep 23 – 30

€ 140 per night
Guest favorite

Apartment in Saint Charles

4.95 out of 5 average rating, 273 reviews

Pop Lucks Guest Suite in Historic Old St. Charles

Welcome to Pop Luck's Guest Suite! This adorable gem represents everything you love about Old St. Charles. This cozy suite is just steps away from the heart of Main Street, restaurants, and all the action St. Charles has to offer. Pop Luck's is a charming one-bedroom, with an open and airy living room and kitchen. It has natural light and high ceilings throughout. It's farmhouse cottage decor makes for a relaxing place to rest. Also, check out our sister suite The Ella Rose, right next door.

Apr 24 – May 1

€ 128 per night
Guest favorite

Guest suite in Saint Charles

4.95 out of 5 average rating, 292 reviews

Creekside Suite - Peaceful, Spacious, and Comfy

Enjoy your stay in a spacious walkout basement-level suite that includes bedroom, bathroom, living/dining room & patio. Bedroom has queen bed, dresser, desk & TV. Living room has futon, books, games & TV. TVs have Netflix. Suite has minifridge, microwave, toaster & coffee-maker. Eat at the dining table or sit up to the window counter to look out on the creek & woodlands behind the house. Situated in a quiet, safe neighborhood with parks & ponds. Just 8 miles from historic downtown St Charles.

Apr 2 – 9

€ 113 per night

Popular amenities for O'Fallon vacation rentals

Stay near O'Fallon's top sights

Ethyl's Smokehouse & Saloon4 locals recommend
The Meadows at Lake Saint Louis6 locals recommend
Sugarfire Smoke House3 locals recommend
Bowlero St. Peters8 locals recommend
The Brass Rail6 locals recommend
McGurk's Public House3 locals recommend

Other great vacation rentals in O'Fallon

Guest favorite

Guesthouse in St. Peters

4.96 out of 5 average rating, 24 reviews

Maple Tree Enchanted Guest House 1 bedroom 2 beds

Sep 3 – 10

€ 94 per night
Guest favorite

Home in O'Fallon

4.96 out of 5 average rating, 24 reviews

Conveniently located, 4 bed, 2.5 bath on quiet Ct

Jan 23 – 30

€ 208 per night
Superhost

Apartment in Saint Charles

4.88 out of 5 average rating, 17 reviews

Stylish Guest Suite in New Town St. Charles

Mar 1 – 8

€ 128 per night
Guest favorite

Home in O'Fallon

4.94 out of 5 average rating, 31 reviews

Blair's House in O'Fallon 3 Bed 1.5 Bath Game Room

Mar 18 – 25

€ 237 per night
Guest favorite

Home in O'Fallon

4.9 out of 5 average rating, 10 reviews

Modern+Family Friendly 3 BR Home

May 6 – 13

€ 269 per night
Guest favorite

Home in Wentzville

5.0 out of 5 average rating, 26 reviews

Spacious (basement) apartment in Wentzville

Nov 7 – 14

€ 157 per night
Superhost

Home in O'Fallon

4.85 out of 5 average rating, 88 reviews

Spacious*Large Outdoor Space*Family*Modern*Artsy

Sep 27 – Oct 4

€ 482 per night
Superhost

Loft in Saint Charles

4.8 out of 5 average rating, 41 reviews

City Loft in Saint Charles

Jun 29 – Jul 6

€ 129 per night
Guest favorite

Home in Saint Charles

4.93 out of 5 average rating, 29 reviews

Cozy Mid-Century Modern Townhome

Aug 3 – 10

€ 136 per night
Superhost

Apartment in Saint Charles

5.0 out of 5 average rating, 5 reviews

Blue Suite @The Painted House

Oct 3 – 10

€ 147 per night
Guest favorite

Home in Wentzville

5.0 out of 5 average rating, 38 reviews

Relax & Enjoy Home~Cozy~Updated~Fence~POND

Aug 2 – 9

€ 224 per night
Guest favorite

Home in O'Fallon

5.0 out of 5 average rating, 19 reviews

Family Getaway Home | private backyard | Office

Aug 23 – 30

€ 360 per night

Quick stats about vacation rentals in O'Fallon

Total rentals

80 properties

Rentals with dedicated workspaces

40 properties have a dedicated workspace

Rentals with a pool

10 properties have a pool

Pet-friendly rentals

30 properties allow pets

Family-friendly rentals

50 properties are a good fit for families

Total number of reviews

3.4K reviews

Frequently Asked Questions

  • Do house rentals in O''Fallon have air conditioning?

    Absolutely! We offer over 60 house rentals with air conditioning in O''Fallon. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in O''Fallon have free parking?

    Absolutely! We offer over 60 house rentals with free parking in O''Fallon. Enjoy a tailored experience with all the comforts you desire.

  • Are there pet-friendly vacation rentals in O''Fallon?

    Four-legged friends are welcome in O''Fallon. Choose from more than 30 vacation rentals for guests traveling with pets.

  • Are there O''Fallon vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 10 vacation homes with pools in O''Fallon, available on Airbnb. Make a splash and soak up the sun in style!

  • Are there family-friendly vacation rentals in O''Fallon?

    O''Fallon has more than 50 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • Are there vacation rentals with a dedicated workspace in O''Fallon?

    Yes! Work meets play with ease at over 40 vacation rentals in O''Fallon featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Where should I stay in O''Fallon?

    Make yourself at home in O''Fallon by choosing from our most frequently booked neighborhoods. We have over 30 vacation rentals in Turtle Creek, and over 60 vacation rentals in Dardenne Farms.

  • Do house rentals in O''Fallon have wifi?

    Absolutely! We offer over 60 house rentals with wifi in O''Fallon. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in O''Fallon have a kitchen?

    Absolutely! We offer over 50 house rentals with a kitchen in O''Fallon. Enjoy a tailored experience with all the comforts you desire.

  • What are the most popular amenities for House Rentals in O''Fallon?

    Enhance your stay in our House Rentals with the most popular amenities: over 60 homes with free parking, over 60 homes with air conditioning, over 50 homes with a kitchen, over 60 homes with wifi, and more. Indulge in the ultimate retreat, tailored to your preferences.

Destinations to explore

  1. Airbnb
  2. United States
  3. Missouri
  4. St. Charles County
  5. O'Fallon