Vacation rentals in La Mesilla

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Top-rated vacation rentals in La Mesilla

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Guesthouse in Velarde

4.95 out of 5 average rating, 287 reviews

Casita del Bosque

Enjoy the quiet of an old adobe casita in a traditional Northern New Mexico village, only a stone’s throw away from a multitude of attractions and activities. Explore our beautiful canyons, rivers, mountains and unique communities in every direction from Lyden. Experience modern-day Pueblo communities, ancient petroglyph sites, scenic drives, National Monuments, hiking/biking trails, birding hotspots, Georgia O’Keefe’s home, mineral springs and local restaurants. More in “Show Host’s Guidebook”!

Jan 29 – Feb 5

€ 118 per night
Guest favorite

Home in Santa Fe

4.94 out of 5 average rating, 110 reviews

Hacienda Cielo de Nambe, Premiere Getaway Location

Unwind in the privacy & beauty of a historic adobe that was lovingly renovated in 2017. Nambe is known for its graceful private homes & is 20 min north of Santa Fe, an easy drive. At the Hacienda, adventures are just out your front door: Bandelier, Nambe Falls, Abiquiu, the Pueblos, just to name a few. Ancient cottonwoods surround the adobe, and the night sky is filled with stars. Please visit & make yourself at home, & create some special memories of your own here in the Land of Enchantment.

Sep 3 – 10

€ 134 per night
Guest favorite

Home in Santa Fe

4.95 out of 5 average rating, 126 reviews

Casita De Nambe

Our cozy 1 bedroom, 1 bathroom home can accommodate 4 guests, and is perfect for an amazing adventure in beautiful Northern New Mexico. Casita De Nambe is located in the heart of Nambe and comes fully equipped for both long or short term stays. Guests are provided with a fully equipped kitchen, stove heater, washer, dryer, WIFI and a smart TV compatible with Netflix & Hulu. The patio is equipped with a grill and a fire pit for outdoor activities as well as a fully gated yard, perfect for pets!

Oct 28 – Nov 4

€ 125 per night

Popular amenities for La Mesilla vacation rentals

Other great vacation rentals in La Mesilla

Guest favorite

Guest suite in Los Alamos

4.94 out of 5 average rating, 289 reviews

Guest Room Suite Private Entrance & Bath

Apr 30 – May 7

€ 97 per night
Guest favorite

Home in Santa Fe

4.98 out of 5 average rating, 902 reviews

Beautiful One Bedroom Casita

Mar 8 – 15

€ 97 per night
Guest favorite

Guesthouse in Abiquiu

4.97 out of 5 average rating, 172 reviews

Pedernal Casita at Abiquiu Lake

Jul 17 – 24

€ 95 per night
Guest favorite

Dome in El Prado

4.9 out of 5 average rating, 1058 reviews

Geodesic Earth Dome

Mar 2 – 9

€ 96 per night
Superhost

Home in Abiquiu

4.83 out of 5 average rating, 364 reviews

Raven House

Aug 5 – 12

€ 120 per night
Guest favorite

Guesthouse in Santa Fe

4.91 out of 5 average rating, 203 reviews

Santa Fe Guest House Sunset Views Private Quiet

Apr 26 – May 3

€ 142 per night
Guest favorite

Apartment in Vadito

4.94 out of 5 average rating, 109 reviews

Farmhouse Casita

Dec 27 – Jan 3

€ 95 per night
Superhost

Guest suite in Abiquiu

4.93 out of 5 average rating, 322 reviews

Star Dance Lodge Moon Casita

Nov 27 – Dec 4

€ 119 per night
Guest favorite

Guesthouse in Dixon

4.92 out of 5 average rating, 450 reviews

Rivers Edge Guest House

Sep 3 – 10

€ 144 per night
Guest favorite

Home in Dixon

5.0 out of 5 average rating, 235 reviews

Stylish cottage in a beautiful canyon on the river

Sep 26 – Oct 3

€ 174 per night
Guest favorite

Cottage in Santa Fe

5.0 out of 5 average rating, 307 reviews

Magical Desert Casita with Hiking Out the Door!

Jan 18 – 25

€ 152 per night
Guest favorite

Guesthouse in Jemez Springs

4.91 out of 5 average rating, 447 reviews

Jemez Springs Cozy Private Cottage

Jul 8 – 15

€ 138 per night

Destinations to explore